SELECTIVE BINDING OF HELIX POMATIA LECTıN TO IMMATURE THYMOCYTES

The Mucoproteins of the Snails, Helix Aspersa and Helix Pomatia

The problem of the structure of complex proteins containing carbohydrates in their molecule is still a subject of discussion. The fundamental questions which have been debated during the last decades and which have been the subject of many controversies are concerned with the nature of the carbohydrate group present in the molecule of these substances. Since the discovery of mucoproteins or muc...

The hydrolysis of glucosaminides by an enzyme in Helix pomatia.

IT has long been known that the polysaccharide chitin when completely hydrolysed yields glucosamine and acetic acid; in recent years it has indeed been shown conclusively that the basic unit of the polysaccharide is N-acetylglucosamine. The evidence for the latter statement rests, firstly, on the discovery by Karrer & Hofmann [1929] ofan enzyme in Helixpomatiawhich is able to hydrolyse chitin t...

Aerobic metabolism of the hepatopancreas of Helix pomatia.

The presence ofthe tricarboxylic-acid cycle (Krebs's cycle) has been demonstrated in most mammalian tissues investigated (Krebs & Johnson, 1937; Green, Loomis & Auerbach, 1948), where it appears to be the major pathway for the oxidation of carbohydrate, fat and protein intermediaries. No detailed examinations have been made in the invertebrates. However, evidence has been presented of Krebs's c...

Identification of O-Linked Glycoproteins Binding to the Lectin Helix pomatia Agglutinin as Markers of Metastatic Colorectal Cancer

BACKGROUND Protein glycosylation is an important post-translational modification shown to be altered in all tumour types studied to date. Mucin glycoproteins have been established as important carriers of O-linked glycans but other glycoproteins exhibiting altered glycosylation repertoires have yet to be identified but offer potential as biomarkers for metastatic cancer. METHODOLOGY In this s...

Studies on the specificity of choline esterase in Helix pomatia.